LOOKING LIKE ABRAHAM LINCOLN A VIDEO ABOUT MARFAN POSSIBLE NEW TREATMENT FOR MARFAN SYNDROME BLOOD PRESSURE DRUG LOSARTAN COZAAR MIGHT PROTECT AORTA

LOOKING LIKE ABRAHAM LINCOLN VIDEO ABOUT MARFAN POSSIBLE NEW TREATMENT FOR MARFAN SYNDROME BLOOD PRESSURE DRUG LOSARTAN COZAAR MIGHT PROTECT AORTA

---

Looking Like Abraham Lincoln What Is Marfan Syndrome? How Might Losartan Cozaar Protect

The blood pressure drug Losartan marketed as Cozaar by Merck, may help defend people with Marfan Syndrome from damage to the aorta, the most important artery in the body. Doctors are currently running clinical trials to test the effectiveness of Losartan for Marfan Syndrome. Scholars have speculated over the years that Abraham Lincoln had Marfan because his appearance seemed to fit the bill for Marfan's.



"People with Marfan Syndrome a genetic condition that can be inherited or, in roughly one-fourth of cases, can appear out of nowhere tend to have long limbs and fingers, are often tall and may encounter a broad range of symptoms". Losartan is a type of blood pressure drug called an angotensin receptor type 2 antagonist. A preliminary study published in the New England Journal of Medicine suggests that Losartan Cozaar may prevent lethal damage to the aorta in people with Marfan Syndrome. The drug may act to slow down aorta growth. The findings have already paved the way for a large-scale trial of the drug for this condition.


Marfan Syndrome is a disorder of connective tissue. Connective tissue holds all the parts of the body together and helps control growth. Connective tissue gets some of its strength from a protein called fibrillin 1. Fibrillin 1 also plays an important role in controlling the growth and development of the body. In Marfan syndrome, the body produces fibrillin 1 that does not work properly. As a result, the connective tissue is not as strong as it should be, and the growth and development of the body are affected.


Watch this video outlining signs of Marfan Syndrome Click the arrow to start





Most people who have Marfan Syndrome have problems with their heart and blood vessels because of weak connective tissue. The aorta is the large artery that carries oxygenated blood from the heart. Marfan can impact the strength of the aorta. The findings have already paved the way for a large-scale trial of the drug for this condition. Previous "research suggested that Losartan slashes circulating levels of transforming growth factor beta, interrupting this cycle of aorta damage. "In the 1990s, cardiologist Harry Dietz of Johns Hopkins University in Baltimore led a team of researchers that discovered that Marfan Syndrome stems from a mutation in the FBN1 gene that encodes a glycoprotein called fibrillin-1. In people with the syndrome, a lack of fibrillin-1 allows excess production of a signaling protein called transforming growth factor beta, which kicks on a host of reactions that damage the aorta walls over time, says research physician Benjamin Brooke of Johns Hopkins. The drug also eases blood pressure, which puts less strain on the aorta itself, studies in mice showed".

Click for healty medical Causes of Exercise Sports Health Problems

Blood pressure drug might offer new treatment for Marfan syndrome

ATENOLOL VS. LOSARTAN CLINICAL TRIAL

Angiotensin II Blockade and Aortic-Root Dilation in Marfan's Syndrome