LOW VITAMIN D AND BREAST CANCER STUDY REPORTS POSSIBLE CONNECTION
Could Vitamin D Levels Be Associated With Breast Cancer Prognosis?
"Women who have a vitamin D deficiency when they are diagnosed with breast cancer were 94% more likely to have their cancer metastasize and 73% more likely to die within 10 years, Canadian researchers have reported. The study represents "the first time that vitamin D has been linked to breast cancer progression," said Dr. Pamela Goodwin of Mount Sinai Hospital in Toronto, who led the study". Vitamin D has been in the spotlight a number of times as having a possible relationship to cancer. For example,in 2006 Harvard and Northwestern scientists illuminated a possible benefit of vitamin D against pancreatic cancer in the journal Cancer Epidemiology Biomarkers and Prevention.
The researchers wrote "We observed that a higher intake of vitamin D was associated with a decreased risk for pancreatic cancer in two large U.S. cohorts". (A cohort is a group of people who share a common characteristic or experience within a defined period (e.g., are born, leave school, lose their job, are exposed to a drug or a vaccine, etc.)
Researchers Looked At Vitamin D Levels
"Women who have a vitamin D deficiency when they are diagnosed with breast cancer were 94% more likely to have their cancer metastasize and 73% more likely to die within 10 years, Canadian researchers reported Thursday.In the abstract they wrote "Vitamin D acts through a nuclear transcription factor to regulate many aspects of cellular growth and differentiation. Low levels have been associated with increased breast cancer risk". We examined Vitamin D levels and prognostic effects in an existing breast cancer cohort".(A cohort is a group of people who share a common characteristic or experience within a defined period (e.g., are born, leave school, lose their job, are exposed to a drug or a vaccine, etc.) The team also found that only 24% of the women in its study had what are normally considered adequate levels of vitamin D at the time of the diagnosis".
"The study represents "the first time that vitamin D has been linked to breast cancer progression," said Dr. Pamela Goodwin of Mount Sinai Hospital in Toronto, who led the study.The results are "very provocative," said Dr. Joanne Mortimer, a breast cancer specialist at City of Hope Comprehensive Cancer Center in Duarte, who was not involved in the study. "There is some evidence that some of the drugs we use to treat breast cancer, such as aromatase inhibitors, need vitamin D to be activated and metabolized.""
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